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The most common form of arthritis is osteoarthritis, sometimes referred to as “wear-and-tear arthritis” because it is characterized by the wearing away of cartilage. Cartilage is the spongy tissue that cushions bone ends and facilitates smooth, pain-free movement of the joints and spine. With normal aging, the body loses its ability to naturally regenerate and repair cartilage, and to maintain synovial fluid in the joints.

Cartilage can also be damaged through extraordinary stress, which can result from strenuous activity such as flyball, or simply from normal activity in large or heavy animals. It can also be damaged by a joint injury or surgery.

Malformation of joints, or “dysplasia”, can also cause premature wearing of cartilage because the bones are not positioned properly. Treating the wearing of cartilage in these cases can help relieve pain and slow joint deterioration. However, it cannot correct the malformation.

When cartilage is damaged, the joint can lose its proper shape resulting in pain, swelling, and stiffness.

Osteoarthritis is progressive.  Left untreated, after many years of cartilage drying out, chipping, and wearing away, the bone ends may actually rub together causing even more pain and further limiting mobility. Prevention and early treatment can keep your pet happily mobile and pain free into their old age. However, even very old, severely arthritic animals can also benefit tremendously from treatment and ongoing maintenance with the DR.MAGGIE™ Extra Strength Joint Formula.

Glucosamine and Chondrointin

Glucosamine stimulates the body’s production of glycosaminoglycans and proteoglycans, two essential building blocks of cartilage. Chondroitin suppresses the catabolic enzymes that break down cartilage, and cause inflammation.

High quality low density Chondrointin can cost many times more than glucosamine, which is why many products use less than an optimal amount, often substituting chondrointin with other less effective anti-inflammatory agents such as MSM, boswellia, devil’s claw, and yucca.

These compounds can provide some anti-inflammatory effect, however, in most cases the dose is well below therapeutic levels.  Potential toxicity levels are largely unstudied.

MSM (Methylsulfonlmethane)

MSM is commonly used in amounts well below the dosages proven to be most effective in studies.  In a double blind placebo controlled 12 week study, subjects experienced statistically significant reductions in joint discomfort when taking 6,000 mg of MSM per day.  This is well below the dosage in most commercial formulations.


Similarly, boswellia  (boswellia serrata) has been shown to provide significant benefits in relieving  joint discomfort and swelling when administered in 3,000 mg, per day.  The levels of boswellia typically found in commercial preparations are a small fraction of this therapeutic amount.

NSAIDs Painkillers and Other Drugs

Many pets are on aspirin or NSAIDS (non-steroidal anti-inflammatory drugs – e.g. Metacam, Rimadyl) before they begin glucosamine/chondroitin therapy. It is advisable to wean them off painkillers over 4 – 6 weeks while the glucosamine and chondroitin are taking effect.  If NSAIDS are discontinued too soon, your pet may experience pain.

Unlike NSAID’s which only mask symptoms, the DR.MAGGIE™ ES Joint Formula actually improves joint function and mobility. It is a much healthier, safer, long-term solution which can restore quality of life.

Some animals with severe arthritis may occasionally need a low dose of buffered aspirin or NSAIDS to maintain comfort even with the benefits of DR.MAGGIE™ ES Joint Formula. Always consult your veterinarian before administering aspirin.

DR.MAGGIESupplement for Skin & Coat, with omega fatty acids, lecithin and vitamins A, E, and D, is an excellent complement to DR.MAGGIE™ ES Joint Formula.

The DR.MAGGIE™ ES Joint Formula provides an optimal amount of the safest, most effective nutrients for the best short and long term results.